Friday

GeneTherapy in Periodontal Treatment.

Wishing all our readers a Happy New Year

Genetherapy has been used in treatment of critical illness which are life threatening and has never used in periodontal disease till some scientists from university of Michigan decided to try it. They tried gene therapy in subjects with rheumatoid arthritis, who are more likely to have periodontal disease. They found out that gene therapy used to treat periodontal disease also showed 30% improvements in pain relief and gain of function.

How dose the gene therapy work:
Tumor necrosis factor is know to be increased in periodontitis with decease in soluble TNF receptor. Using gene therapy, Giannobile's group found a way to help certain cells using an inactivated virus to produce more of a naturally-produced molecule soluble TNF receptor. This factor is under-produced in patients with periodontitis. The molecule delivered by gene therapy works like a sponge to sop up excessive levels of tumor necrosis factor, a molecule known to worsen inflammatory bone destruction in patients afflicted with rheumatoid arthritis, joint deterioration and periodontitis.
The gene could potentially work for long period of time and can have life-long treatment effects in patients with risk for severe disease activity.


Adapted from
Gum Disease. ScienceDaily. Retrieved January 2, 2009, from http://www.sciencedaily.com­ /releases/2008/12/081211081448.htm

2 comments:

Dave Leader said...

This is cutting edge without the blade. When could this kind of therapy become routine?

Perio Talk said...

Presently this is undergoing further human trials to check for safety. It is not far that such technology will be at your chair side to help evry common man.

Invitation

If you have any views news or product information to be shared on PerioTalk.
  • Mail them here
  • Archives

    Labels

    3D dentures (1) Alzheimer’s disease (1) Anorexia (1) Atena dental plans (1) B Cell (2) bad breath (1) bangkok dental services (1) biofilm (1) bisphosphonates (1) bleeding gums (1) Bone resorption (1) brush (1) brushing (2) Bulimia (1) C-reactive protein (5) checkdent (1) Coenzyme10 (1) comfort dentistry (1) Concious Sedation in Dentistry (1) CoQ10 (1) DDS. (3) dental abcess (1) Dental Admission Test (1) dental assistants (1) dental biofilm (1) dental care (1) dental decks (1) dental ebooks (2) dental education (1) dental emergencies (1) Dental Health Games for Kids (1) dental hygienist (1) Dental Implant (8) dental implants (3) dental insurance (1) dental lab (1) dental malpractice (1) Dental Malpractice Attorney (1) dental network (1) dental office (1) dental office software (1) dental plan (1) dental plaque (1) dental school (2) dental school application (1) dental schools (1) dental tourism (2) dental veneers (2) dentistry (5) development (2) diabetes (2) diet (1) edentalmagazine (1) electric toothbrush (1) Emdogain (1) Free Text Books (4) gum disease (2) gum problems (1) heart disease (2) immune response (1) insurance plans (1) Invisaling (1) kids brushing (1) Liability Insurance (1) life after dental school (1) markers (2) marketing strategies (1) mesothelioma (1) mesothelioma information (1) mesothelioma laws (1) nbde (1) New Inventions (5) obesity (1) online dental textbooks (4) OPG (2) oral and sytemic links (16) oral cancer (1) oral health (2) oral irrigator (1) oral microorganism (2) orthodontics (2) osteonecrosis (1) osteoporosis (1) Patient info (10) payroll checks (1) periodontal disease (17) periodontal pathogens (3) Periodontal surgery (7) periodontics (1) periodontist (1) periodontitis (7) periotalk (2) PGRF (1) PhD (2) Piezosurgery (3) Plasma Rich in Growth Factor (1) preterm birth (2) product review (1) RANK (3) RANKL (3) room booking software (1) saliva (3) sedation dentistry (2) Sensitive Tooth (1) Sinus lift (4) social dentistry (1) stages of plaque formation (1) stress (1) stroke (1) surgical guide (1) T cell (2) teeth (4) Teeth Whitening (1) therabreath (1) therapeutic (5) treatment (6) university of sydney (1) veneers (2) video (13) what after BDS (1) Whats New?? (14)

    infinity