Tuesday

In Search of Markers!

Researchers have been trying to find markers for health and disease. Markers help in diagnosing the presence or the risk of a certain disease. Markers for periodontal health or disease has been elusive.
Saliva has been researched in recent times to find markers for cardiovascular disease, stress, preterm birth(refer to my earlier post),and periodontal disease. We know the advantage of using the saliva being most noninvasive and easy to obtain compared to blood or gcf samples. Various cytokines like the IL-1, IL-6,IL-10 and Matrixmetalloproteinase levels are suggested as possible markers.
Wouldn't availability of a certain marker make the life of the clinician so simple....to diagnose presence or absence of periodontal disease. The study below is one such attempt to search for the elusive marker.

Correlation between salivary IL-1beta levels and periodontal clinical status.

Tobón-Arroyave SI, Jaramillo-González PE, Isaza-Guzmán DM. (Link to abstract)

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