Thursday

In Hibernation!

I have not spent much time on this blog recently because of my course work and midterm exams. I should be active on this after 20th Oct 2006.
Meanwhile I just wanted to share a interesting Question from one of the Groups that I subscribe to:

Question:

Is there any significant relationship between serum lipid level &
periodontitis or vice versa?


My Answer:

There is a strong correlation between the obesity, diabetes,
inflammation, CRP and artherosclerosis.
Periodontal disease causes increase in the CRP levels (in response to
IL6). Obesity causes insulin resistance and so dose increased
inflammatory mediators. Now where am getting to??

In obese subjects the major source of IL6 is from adipocyte, and also
the LPs from the periodontal organism can increase the IL6 production,
this drives up the CRP level in the blood, leading to the various
effects of CRP. Adipocytes also play a important role in inflammation by
production of TNF alpha and thus leading to insulin resistance.

With this small piece of information are we able to derive a
relationship between the serum LDL and Periodontitis???? U decide.

Readers please leave your comments to the question, what you think......

1 comment:

Anonymous said...

hi Dr. Vinayak its nice to see your thought on relationship between obesity, diabetes and periodotitis. can you place some refrence for same.
thanks jay

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