Thursday

Saliva for Diagnosis

As dentist we all have heard "Mouth" being quoted as the mirror or an index of the general health, so then saliva could prove to be an important component of this index. The reports form the study done by Menon et al (2006) on salivary protienases found elevated Matrix meatloprotienases (MMP) activity, especially MMP9 activity in premature rupture of membarne(PROM) in preterm delivery. The report the potential use of salivary proteinase activity for predtictive test for PROM before preterm delivery.
Unlike GCF saliva is found in larger quantities. Saliva is a mixture of the GCF along with its own MMP and cytokines, continously bathing the tissues in the oral cavity. Analyzing the MMP and the cytokine in the saliva and corelating it should help in saliva emerging as a important tool for diagnosis.
.... so are my views at this point in time.

article quoted: Menon, Ramkumar; McIntyre, J Oliver; Matrisian, Lynn M; et al.
Salivary proteinase activity: a potential biomarker for preterm premature rupture of the membranes.
Am J Obstet Gynecol 194 (6) : 1609-15; discussion 1615 2006 Jun

1 comment:

Anonymous said...

hi there , i am actually on preparing a presentation on pre-term delivery and periodontitis , the article that u proposed looks so good , i'm a new member in Yahoo group of periodontology , my name is Mohamed Hamze , thank u ..

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